Current Issue : January-March Volume : 2012 Issue Number : 1 Articles : 5 Articles
Diabetes mellitus is a serious illness with multiple complications and premature mortality, accounting for at least 10% of total health care expenditure in many countries. Bauhinia variegata Linn. grow in subtropical and tropical climate. The chemical constituents present in the plants are β-sitosterol, luperol, kemferol-3-glucoside, tannins, carbohydrates, amines, reducing sugars, quarcetin, rutin. Bark is used as alternative tonic, haematinic, anthelmentic, antibacterial and astringent. Buds are used in cough and bleeding piles. This plant is traditionally used as folk medicine for the treatment of diabetes however no research work has been carried out so far to determine its antidiabetic potential so the present study was undertaken to investigate antidiabrtic potential of leaves of Bauhinia variegata (BV). Wistar albino rats (150-180 gm) of either sex were maintained under standard environmental laboratory conditions and fed with laboratory diet and water ad libitum. The experimental diabetes was induced in the animals by single intraperitonial injection of freshly prepared solution of Streptozotocin (50 mg/kg). The blood glucose level was estimated after 72 hr of Streptozotocin administration. Rats fasting blood glucose level above 200 mg/dl were considered as diabetic and selected for the further activity. Treatment with extracts of BV was started 72 hr after Streptozotocin injection. On the day 21, blood was collected by retro orbital puncture under mild chloroform anesthesia from overnight fasted rats for the estimation of biochemical parameters (e.g. SGOT, SGPT, Cholesterol, Triglycerides, Total protein, Albumin and HDL-Cholesterol). Results of present study reviles that ethanol extract of Bauhinia variegata leaves showed potent blood glucose lowering activity in diabetic rats at the dose of 300 mg/kg. Administration of EE extract of Bauhinia variegata leaves for 21 days not only significantly lowered elevated blood glucose level in diabetic rats but also causes improvement in lipid profile and body weight of the diabetic rats....
Antimicrobial activity of aqueous, ethanol, methanol and chloroform leaf extracts of V.cinerea was evaluated against Enterobacter aerogenes, E.coli, Streptococcus aureus, Proteus vulgaris, Helicobacter pylori, Candida albicans, Aspergillus flavus, and Trichosporan asahi, at different concentrations of 25 µg, 50 µg, 75 µg and 100 µg respectively. Chloramphenicol and Ketoconazole were used as positive control. The results obtained showed that all the extracts exhibited antimicrobial activity. Among the extracts the ethanol extract exhibited more significant activity against most of the pathogens....
The plant Acacia leucophloea Roxb is reported to have great medicinal value in Indian medicine. The present study deals with the preliminary phytochemical screening of Acacia leucophloea Roxb, in vivo evaluation of antipyretic activity of methanol extract by using yeast-induced pyrexia method. The effect of methanol extract of leaves shows that different doses caused lowering of the body temperature up to 2 h following its administration. The effect of methanol extract on yeast-induced pyrexia shows that the rectal temperature was markedly elevated to 38.24°C, 24h after the subcutaneous injection of yeast suspension, decreased to 37.23°C within 30 minutes of leaves extract (100mg/kg) treatment respectively. Leaves extract are producing significant antipyretic activity against the yeast-induced pyrexia model, hence the extract favours antipyretic activity....
Herbs have been the basis of many traditional medicines throughout the world since a long time and continue to provide remedies to mankind. It is basic source of medicine since beginning of human civilization. The recent article provides the information on Lagenaria siceraria (Mol) standl. commonly known as bottle guard which has been widely used as vegetable in India and is a good source of vitamins and minerals forming an excellent diet. The fruit pulp is pharmacologically studied for its cooling, diuretic antibilious, anticancer, antihyperglycemic, antihyperlipidemic and analgesic properties. Fruit is also reported to contain different amino acids, sterols (fucosterol, campesterol), flavone c-glycoside and legenin. This review presents the available literature on Lagenaria siceraria with respect to its ethnobotany, pharmacognostics, phytoconstituents, traditional uses and its pharmacological activity. This article will be helpful and informative for raising the interest in producing new formulations having economic value and useful for mankind....
Melaleuca leucadendron (Linn.), (Myrtaceae) endemic to western part of Maharashtra, were collected from Mumbai.The essential oil (cajeput oil) was hydro distilled by using Clevenger apparatus. Cajeput oil has been historically reported for its antiseptic and anti-inflammatory actions. The antimicrobial activity of the essential oil was evaluated using Well-Agar plate diffusion method and the minimum inhibitory concentration (MIC) was determined. The essential oil was observed to be effective against both gram-positive and gram-negative bacteria; the essential oil is most effective against Bacillus subtilis and Staphylococcus aureus whereas the MIC for Pseudomonas aeruginosa and Escherichia coli was observed to be 5% and 10% respectively. The result suggests that the essential oil of this variety of Melaleuca leucadendron possess constituents with antibacterial properties and thus has a potential for use as an antibacterial agent....
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